Drug Substance Manufacturing Drug Substance Manufacturing
Batch Automation

Batch Automation

Continuous Improvement Through Batch Automation

Our Batch Automation solutions provide greater agility, cost-efficiency and compliance technologies, modernizing manufacturing for both regulatory compliance and continuous improvement.

Rely on our Batch Automation innovations for S88 control hierarchy, campaigns, unit-level alarm management, agile docs and info batch reporting integration, data integrity across batch productions, and CFR21 11 compliance support.

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Choose modular and scalable solutions
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Reduce human error and manual labor
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Use recipe-based batch procedures
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Simplify validation
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Ensure replicable controls
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Ensure version control and audit-trail
Process Instrumentation

Process Instrumentation

Advanced Instrumentation & Final Control Technology

Our Process Instrumentation and valve innovations provide single-source measurement and final control solutions to increase manufacturing plant efficiency, reliability and product quality.

Best-in-class Process Instrumentation and final control technologies enhance performance and outcomes with elements such as diagnostics and self-calibration, aseptic and sanitary solutions, as well as general service and the most difficult applications. Diagnostics drive reliability, maintenance scheduling/planning, parts and effective troubleshooting. 

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Ensure accurate and repeatable measurement and control
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Choose proactive asset management
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Promote maintenance planning and decrease maintenance costs
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Decrease miscommunication and wasted effort
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Lower labor time
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Reduce start up time and cost to commission
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Leverage real-time input for better decision making and resources utilization
Operations Management

Operations Management

Result-Driven Operations Management

Our Operations Management solutions address operations along your supply chain, from the managing of raw materials through the distribution of final product. We help you with everything from developing requirements to implementation, along with staff training and support, ensuring you meet all of your manufacturing goals.  

This transformative process reduces human error and enforces compliance, eliminates resource-intensive paper systems, simplifies integration of data from automated systems, improves handling of variations in operations, and provides valuable, real-time operational monitoring and alerts. 

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Ensure repeatable and reliable operational systems
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Use electronic systems to make record keeping simple and easy to manage
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Leverage flexible operational tools to provide contextualized situational awareness to respond to system variations
Compliance and Data Management

Compliance and Data Management

Accurate, Complete and Repeatable Data

Our Compliance and Data Management solutions help keep your data accurate, complete and repeatable. This advances your decision making, efficiencies and processes for optimal outcomes, greatly reducing deviations and release times.

You can count on our specialists to assist you with everything from developing requirements to implementation, with all the necessary staff training and support to help you meet all of your goals. This best-in-class technology and expertise will ensure you shorten product time to market, enhance data integrity and product quality, and maintain repeatable and reliable operations.

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Choose robust and reliable electronic systems to meet compliance with regulations
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Reduce burden on resources and risk of quality errors
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Provide critical data to the right people efficiently for timely, compliant accurate decisions
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Leverage record data integrity to ensure product quality
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Minimize time to market and increase profitability
Production Scheduling

Production Scheduling

Advanced Planning and Scheduling

Our advanced Production Scheduling solutions meet the demand for increased efficiencies and data integration for various operations and automation data sources. Facility Fit innovations identify conflicts and constrains prior to technology transfer, while flexible configurations promote seamless integration with existing data and automation infrastructure.

These scheduling and planning innovations leverage real-time modeling to improve quality, productivity, flexibility and manageability of manufacturing facilities, while accounting for variability in processes.

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Gain insight into manufacturing variability
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Streamline automation and operation systems, including new system introductions
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Maximize production throughput capacity and resource output
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Identify, evaluate, and mitigate process constraints and manufacturing scheduling conflicts, while streamlining other critical activities
Process Analytical Technology

Process Analytical Technology

Cutting-Edge Process Analytical Technology

Our Process Analytical Technology (PAT) solution helps drive new ways to design, analyze and control manufacturing processes by measuring critical raw and processed material quality and performance attributes. Becoming more efficient while reducing over-processing enhances efficiency and minimizes waste, ultimately ensuring final product quality.

Through our PAT innovations, we'll help you optimize processes, decrease release times and WIP, simplify disparate automation systems, enhance regulatory compliance, establish agile and flexible start-to-finish manufacturing facilities, reduce time to market, achieve reduce tech transfer and scaling solutions, and embrace digital transformation, Industry 4.0 and IoT adoption.

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Reduce batch variability
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Stay globally competitive
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Decrease release times and WIP
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Make real-time informed and responsive decisions
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Increase yield with innovative technologies
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Shorten time to market
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Achieve operational excellence, while staying within resource, manufacturing and compliance constraints
Calibration and Instrumentation Management

Calibration and Instrumentation Management

Our Calibration and Instrumentation Management solutions deliver the highest levels of precision, reliability and quality in drug substance production.

Through state-of-the-art calibration and instrumentation technology, we'll help you track all instrument configurations, monitor changes with the ability to roll back to previous configurations, automatically identify potential issues through diagnostics, and seamlessly issue work orders through CMMS. Additionally, you can effortlessly confirm correct instrumentation, provide input to scheduling and planning, commission devices and loop checks, monitor and correct diagnostics, and calibrate and repair valves and instruments on-site or off-site.

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Increase accuracy and reduce cost of instrument and valve configuration management to meet compliance requirements more cost effectively
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Switch to predictive maintenance versus time-based maintenance to save effort and money
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Streamline maintenance with diagnostic data-driven automated work orders
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Utilize expertise to determine corrective actions to minimize troubleshooting and down time
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Reduce start-up time and cost to commission
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Leverage diagnostics to help eliminate unplanned downtown
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Provide real-time data to production planning to increase multi-discipline productivity, plant overall uptime and throughput
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Repair valves and instruments back to factory specifications for compliance and optimal operations, minimizing downtime and maximizing productivity
Essential Asset Monitoring for Predictability

Essential Asset Monitoring for Predictability

Our Essential Asset Monitoring solution improves equipment reliability, including pumps, heat exchangers, blowers, compressors, pipes and vessels, cooling towers and other types of equipment.

These innovations help you avoid production loss by predicting failures through diagnostics and AI analysis, cost-effective pervasive sensing, genre-focused mobile apps and tools, and connection to CMMS, ER/P, and scheduling applications.

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Increase production throughput by decreasing unplanned downtime
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Reduce spare part inventory by ordering parts based on requirement predictions
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Predict, plan and utilize downtime affectively across multiple disciplines using real-time data
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Use real time production schedule input to better utilize resources and avoid miscommunications
Flexible Automation Production Solutions

Flexible Automation Production Solutions

Our Flexible Automation production solutions allow you to strategically adjust with your process and demand, reduce and fix production costs, improve quality, and eliminate health and safety issues.

This automation innovation provides you S88 recipe-based structure for easy reconfiguration and product change-overs in a regulatory compliant manner. Plus, you gain modular hardware with plug-and-play field interchangeable I/O, built-in, easy-to-use advanced diagnostics, advanced control and tools, a solution built for PAT, built in tools for compliance, IoT integration, data integrity with flexibility, the ability to execute and manage solution deliveries in a predictable compliant manner, and lifecycle support.

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Decrease operating and expense costs by running multiple products, experiments, or campaigns utilizing the same assets
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Decrease WIP by allowing quick compliant changeovers and release by exception
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Increase throughput and ROI by reducing downtime for compliant upgrades over life cycle of assets
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Cut unplanned downtime and operational costs, and increase schedule reliability by enabling asset health and diagnostics
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Identify and deliver targeted ROI utilizing correct technology and approach
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Reduce time to market and scale up by moving to real-time release and release by exception
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Minimize assay time and error through embedded PAT for in-line measurement and control
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Ensure correct quality data for compliance
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Use solutions to best fit needs predictably and on schedule

Talk to one of our experts

724-746-3700
Get in touch with an expert, find the nearest ECI location or send us a note about your next project.
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